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Motrin Stevens-Johnson Syndrome Lawsuit Allowed to Proceed

Shezad Malik MD JD

A Children’s Motrin product liability lawsuit has been allowed to move forward.

The plaintiffs allege that Johnson & Johnson failed to warn about the risk of serious and potentially deadly skin problems from Motrin.

 

 

SJS News

After sudden ailment, family says daughter healing amazingly well

Within hours, they said doctors became sure it was Stevens-Johnson Syndrome (SJS). The Manches took Hannah to United Hospital in the Twin Cities, which soon recommended she go to Regions’ specialized burn unit. Kathy and Johnny say each step of the medical decision making was crucial to their daughter’s health.

Her skin had begun to severely blister, leaving her dangerously susceptible to infection. SJS is an uncommon skin disorder in which less than 30% of the skin and/or mucous membranes blister and/or detach. Hannah’s condition worsened into toxic epidermal necrolysis (TENS) and affected her entire body, inside and out.

 

Emergency Medicine News & Articles

 

Top Searched Emergency Medicine Articles on -stevens-johnson syndrome-

1 Management of Ocular Conditions in the Burn Unit: Thermal and Chemical Burns and Stevens-Johnson Syndrome/Toxic Epidermal NecrolysisJournal of Burn Care & Research, July 29, 2011 Lin A et al.- Patients in burn intensive care units suffer from potentially life-threatening conditions including thermal or chemical burns and stevens-johnson syndrome/toxic epidermal necrolysis. There is often involvement of the ocular surface or adnexal structures which may be present at the time of hospital admission or may develop later in the hospital course. The article will describe the types of ocular burns, the mechanisms and manifestations of stevens-johnson ...

2 Stevens-Johnson syndrome after lenalidomide therapy for multiple myeloma: a case report and a review of treatment options Hematological Oncology, June 27, 2011 The authors describe a patient with stevens- johnson syndrome (SJS) while receiving lenalidomide in combination with prednisolone for treatment-naïve multiple myeloma. Although SJS has been reported rarely as an adverse reaction to Lenalidomide, this drug should be considered in the etiology of SJS, and the increased number of prescriptions of Lenalidomide for the therapy of multiple myeloma has to stress the awareness of its potentially serious side-effects.

3 Fatal bronchiolitis obliterans complicating Stevens-Johnson syndrome following treatment with nimesulide: a case report Annals of Tropical Paediatrics: International Child Health, July 27, 2011 Dogra S et al. - Nimesulide is a frequently used non-steroidal anti-inflammatory drug with analgesic and antipyretic effects in children. In view of fatal adverse drug reactions, however, its safety has been questioned. A 5-year-old boy developed stevens-johnson syndrome following use of nimesulide which was later complicated by rapidly progressive fatal bronchiolitis obliterans.

4 Boston ocular surface prosthesis: An Indian experience Indian Journal of Ophthalmology, June 13, 2011 Rathi VM et al. - Boston ocular surface prosthesis (BOSP) improves visual acuity (VA) in patients who have irregular astigmatism as in ectasias and rigid gas permeable (RGP) failures and improves vision and symptoms in patients with stevens-johnson syndrome (SJS).

5 HLA-B*1502 Strongly Predicts Carbamazepine-Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Thai Patients with Neuropathic PainPain Practice, June 17, 2011 Kulkantrakorn K et al. - HLA-B*1502 is a strong genetic marker for CBZ-induced SJS/TEN in Thai patients with neuropathic pain. The screening for this marker should be performed prior to initiation of CBZ treatment to assess the risk of this serious side effect.

Methods This is a case control study to describe the clinical characteristics of SJS/TEN in Thai patients with neuropathic pain who were treated with CBZ, and to determine the association of HLA-B*1502 in ...