What can trigger Stevens Johnson Syndrome

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Stevens-Johnson syndrome: current trends
in management.

Authors: ANZ JOURNAL OF SURGERY   Vol. 77  Issue 8  Aug  2007 
Dalli, Rachel L, Kumar, Rohit, Kennedy, Peter Maitz, Peter Lee, Stephen Johnson, Rae

Affiliation: Burns Unit, Concord Repatriation General Hospital, Sydney, New South Wales, Australia. rdalli@gmp.usyd.edu.au


Abstract: BACKGROUND: Toxic epidermal necrolysis care (TEN) is an uncommon but potentially life-threatening condition that involves sloughing of the skin at the dermoepidermal junction. TEN is a well-recognized syndrome and is part of a range of severe mucocutaneous intolerance reactions, mostly elicited by drugs and/or their metabolites. Reported mortality rates vary widely from 20 to 75%. Several systemic treatment protocols for TEN have been published; however, none has been formally standardized in a randomized controlled trial. The present study documents the current management principles and trends seen in 16 patients admitted with TEN or Stevens-Johnson syndrome over a 5-year period at the Concord Repatriation General Hospital Burns Unit...

 


PreMedline Identifier (PMID): 17635282
Abstract from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine  |  
Study of a Potential New Treatment for Patients With Toxic Epidermal Necrolysis (TEN)
This study is currently recruiting participants.
Verified by Loyola University, January 2010
First Received: September 5, 2006   Last Updated: January 28, 2010  
Sponsor: Loyola University
Information provided by: Loyola University
ClinicalTrials.gov Identifier: NCT00372723