Dilantin May Be Among Cerebral Atrophy Causes

Dilantin anti-convulsant medicine is linked to cases in which epilepsy patients developed cerebellar atrophy.

Dilantin can cause a hard time walking or maintaining balance. Case studies suggest that long-term use of Dilantin phenytoin may lead to cerebellar atrophy.

One study documented cerebellar degeneration in five different patients who had been taking phenytoin. These patients all had high levels of phenytoin in their blood.

At the same time, none of them was having seizures of a type that could lead to hypoxia-induced degeneration.

While the researchers acknowledged that hypoxia associated with seizures can cause cerebral atrophy, they proposed that phenytoin itself may also be a cause.