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Topamax

Topamax

Manufacturer: Ortho McNeil Pharmaceuticals

Generic Name: Topiramate

Topiramate is an anti-seizure medication (anticonvulsant) that works in several ways to prevent seizures and migraines.

Topiramate is used to treat epilepsy and to prevent migraine headaches. For epilepsy, topiramate can be used alone or in combination with other epilepsy medications. For migraine prevention, topiramate is used to treat adults who have 4 or more migraine headaches a month and who have not responded to, or cannot take, medications that treat an acute migraine attack.

Date Created: 11/30/2001
Revised Date: 03/17/2006

September 26, 2001

IMPORTANT DRUG WARNING
Dear Healthcare Professional:

We have updated the prescribing information for TOPAMAX to provide new information about an ocular syndrome that has occurred in patients receiving topiramate.

This syndrome is characterized by acute myopia and secondary angle closure glaucoma. This information is based on postmarketing experience in more than 825,000 patients.

As of August 17, 2001 there have been 23 reported cases: 22 in adults and 1 in pediatric patients. It is generally recognized that postmarketing data are subject to substantial under-reporting...

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