Generic Name: Topiramate
Topiramate is an anti-seizure medication (anticonvulsant)
that works in several ways to prevent seizures and migraines.
Topiramate is used to treat epilepsy and to prevent migraine headaches.
For epilepsy, topiramate can be used alone or in combination with other
epilepsy medications. For migraine prevention, topiramate is used to
treat adults who have 4 or more migraine headaches a month and who have
not responded to, or cannot take, medications that treat an acute
Date Created: 11/30/2001
Revised Date: 03/17/2006
September 26, 2001
IMPORTANT DRUG WARNING
Dear Healthcare Professional:
We have updated the prescribing
information for TOPAMAX® to provide new information about an ocular
syndrome that has occurred in patients receiving topiramate.
syndrome is characterized by acute myopia and secondary angle closure
glaucoma. This information is based on postmarketing experience in more
than 825,000 patients.
As of August 17, 2001 there have been 23 reported cases: 22 in adults
and 1 in pediatric patients. It is generally recognized that
postmarketing data are subject to substantial under-reporting...
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